Wound Healing


Explora's senior management has decades of industry experience in cancer drug development. Our scientists routinely conduct contract research using xenograft models for industry as well as academic scientists. We also maintain rigorous cell culture procedures to ensure consistency in the quality of our cell lines.

Explora BioLabs offers rodent models for wound healing studies. These mouse and rat full thickness excisional dermal models are commonly used to assess dermal wound healing processes, including granulation, tissue deposition, re-epithelialization and angiogenesis.

Dermal wound healing studies can be performed in normal healthy animals, as well as in animals with impaired wound healing. Impaired would healing models include diabetic animals, such as db/db mice. In addition, agents such as steroids can be used to delay the wound healing process.

 Explora’s research team has:

  • Extensive hands-on experience in wound healing studies
  • Excellent technical and surgical capability
  • Established IACUC protocols

Dermal Wound Healing Efficacy Models

  • Excisional
    1. Normal wound healing model – performed with normal animals
    2. Impaired wound healing model – performed with diabetic animals
  • Delayed wound healing studies in mice and rats

Dermal DMPK

  • Pharmacokinetics/ toxicokinetics for dermal/ transdermal routes of administration
  • Radiolabeled or non-radiolabeled test articles