Our experience includes:
  • Non-GLP safety assessment of small molecules and biologics
  • Maximum-tolerated dose (MTD)
  • Dose-range finding (DRF)
  • Acute toxicology
  • Sub-chronic toxicology (repeated dose)
  • Established study protocols

Assessments:

  • In-life clinical observations
  • Sample collection for clinical chemistry, hematology, urinalysis, etc.
  • Comprehensive necropsy
  • Blood sampling
  • Histopathology

Animal Species:

  • Rat
  • Mouse

Drug Administration Routes:

  • IP, IV, IM, SC, PO
  • Arterial
  • Continuous infusion using mechanical or osmotic pumps
  • Nasal mucosa, nasal cavity, or tracheal/bronchial (including aerosol-inhalation)